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Marcelo G Roma Selected Research

estradiol-17 beta-glucuronide

7/2007Disruption of function and localization of tight junctional structures and Mrp2 in sustained estradiol-17beta-D-glucuronide-induced cholestasis.
4/2005Silibinin prevents cholestasis-associated retrieval of the bile salt export pump, Bsep, in isolated rat hepatocyte couplets: possible involvement of cAMP.
8/2003Estradiol-17beta-D-glucuronide induces endocytic internalization of Bsep in rats.

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Marcelo G Roma Research Topics

Disease

35Cholestasis
04/2022 - 04/2002
4Liver Diseases (Liver Disease)
02/2019 - 05/2008
2Non-alcoholic Fatty Liver Disease
01/2019 - 11/2018
2Mitochondrial Diseases (Mitochondrial Disease)
01/2019 - 11/2018
2Chemical and Drug Induced Liver Injury
11/2018 - 02/2016
2Body Weight (Weight, Body)
06/2007 - 05/2004
1Albuminuria
04/2022
1Cystic Fibrosis (Mucoviscidosis)
02/2019
1Cholelithiasis
02/2019
1Biliary Liver Cirrhosis (Primary Biliary Cirrhosis)
02/2019
1Sclerosing Cholangitis
02/2019
1Wounds and Injuries (Trauma)
01/2019
1Iron Overload
01/2019
1Insulin Resistance
01/2019
1Obesity
11/2018
1Fatty Liver
11/2018
1Hepatitis
02/2016
1Prostatic Neoplasms (Prostate Cancer)
02/2016
1Hepatitis C
06/2014
1Porphyria Cutanea Tarda
06/2014
1Acquired Immunodeficiency Syndrome (AIDS)
08/2008
1Infections
08/2008
1Malaria
08/2008
1Leprosy (Hansen's Disease)
08/2008
1Reperfusion Injury
01/2008
1Hepatolenticular Degeneration (Wilson's Disease)
01/2008
1Hyperbilirubinemia
07/2007

Drug/Important Bio-Agent (IBA)

9Multidrug Resistance-Associated Protein 2IBA
02/2018 - 08/2003
8Bile Acids and Salts (Bile Acids)IBA
04/2022 - 04/2002
8Estradiol (Delestrogen)FDA LinkGeneric
04/2018 - 12/2008
8Member 11 Subfamily B ATP Binding Cassette TransporterIBA
02/2018 - 04/2005
6Pharmaceutical PreparationsIBA
01/2021 - 01/2006
5Proteins (Proteins, Gene)FDA Link
02/2018 - 01/2005
5Protein Kinase CIBA
04/2016 - 12/2008
5Estrogens (Estrogen)FDA Link
06/2013 - 07/2003
3Ursodeoxycholic Acid (Urso)FDA LinkGeneric
10/2019 - 12/2010
3Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA
04/2016 - 10/2010
3estradiol-17 beta-glucuronideIBA
07/2007 - 08/2003
3SilymarinIBA
01/2006 - 07/2003
2Complement System Proteins (Complement)IBA
10/2021 - 07/2007
2LipopolysaccharidesIBA
10/2020 - 10/2019
2BilirubinIBA
01/2019 - 02/2014
2Mitogen-Activated Protein KinasesIBA
06/2017 - 03/2014
2Actins (F Actin)IBA
06/2017 - 06/2006
2Estrogen Receptor alphaIBA
04/2016 - 03/2014
2Phosphotransferases (Kinase)IBA
04/2016 - 03/2014
2Protein Kinases (Protein Kinase)IBA
04/2016 - 01/2005
2Proto-Oncogene Proteins c-akt (Protein Kinase B)IBA
03/2014 - 10/2010
2DapsoneFDA Link
08/2008 - 04/2002
2AluminumIBA
01/2008 - 06/2007
2Taurolithocholic AcidIBA
04/2005 - 07/2003
1Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA
04/2022
1AntioxidantsIBA
04/2022
1CreatinineIBA
04/2022
1EnzymesIBA
01/2021
1Spironolactone (Aldactone)FDA LinkGeneric
10/2020
1Phospholipids (Phosphatides)FDA LinkGeneric
02/2019
1EndotoxinsIBA
01/2019
1Fatty Acids (Saturated Fatty Acids)IBA
01/2019
1Nonesterified Fatty Acids (NEFA)IBA
01/2019
1Glucose (Dextrose)FDA LinkGeneric
01/2019
1Heme Oxygenase-1IBA
01/2019
1Triglycerides (Triacylglycerol)IBA
01/2019
1CytokinesIBA
01/2019
1Hemin (Panhematin)FDA Link
01/2019
1GlucuronidesIBA
04/2018
1Insulin-Like PeptidesIBA
02/2018
1ErbB Receptors (EGF Receptor)IBA
04/2016
1src-Family KinasesIBA
04/2016
1Cyproterone AcetateIBA
02/2016
1Adrenal Cortex Hormones (Corticosteroids)IBA
02/2016
1G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA
03/2014
1Cyclic NucleotidesIBA
03/2014
1Cyclic AMP-Dependent Protein Kinases (cAMP-Dependent Protein Kinase)IBA
03/2014
1Mitogen-Activated Protein Kinase Kinases (MEKs)IBA
03/2014
1Adenylyl Cyclases (Adenylyl Cyclase)IBA
03/2014
1Cyclic AMP (AMP, Cyclic)IBA
06/2013
1Alanine (L-Alanine)FDA Link
06/2013
1Albuterol (Salbutamol)FDA LinkGeneric
06/2013
1Glucagon (Glukagon)FDA Link
06/2013
1Hormones (Hormone)IBA
06/2013
1Estrogen ReceptorsIBA
01/2012
1p38 Mitogen-Activated Protein KinasesIBA
01/2012
1ursodoxicoltaurineIBA
12/2010
1Taurochenodeoxycholic AcidIBA
12/2010
1carbazoleIBA
10/2010
1Phosphatidylinositols (Phosphatidylinositol)IBA
10/2010
1Protein Isoforms (Isoforms)IBA
12/2008
1Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA
05/2008
1Transcription Factors (Transcription Factor)IBA
05/2008
1CopperIBA
01/2008
1OccludinIBA
07/2007
1Free RadicalsIBA
06/2007
1Vitamin EFDA LinkGeneric
06/2007
1Aluminum Hydroxide (Algeldrate)FDA Link
06/2007
1GalactosamineIBA
06/2006
1Uridine Diphosphate (UDP)IBA
06/2006

Therapy/Procedure

2Therapeutics
10/2019 - 06/2002
1Ligation
01/2019
1Polypharmacy
11/2018